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Both membranous stain intensity and percentage of tumour cells stained are critical for CLDN18.2 reporting1
In addition to membranous stain intensity and percentage of tumour cells stained, it is recommended that the biomarker report also include:
Integrated reporting:
- The type of testing method used
- A description of the status of the sample, such as “positive,” “negative,” or “inconclusive”
- Any relevant notes or observations regarding the sample or results
How to Report CLDN18.2
Kristina A. Matkowskyj, MD, PhD
References: 1. Pellino A, Brignola S, Riello E, et al. Association of CLDN18 protein expression with clinicopathological features and prognosis in advanced gastric and gastroesophageal junction adenocarcinomas. J Pers Med (Epub) 10-26-2021.